Cover Feature: Study of Carbamoyl Fluoride: Synthesis, Properties and Applications (Chem. Eur. J. 43/2022)

Carbamoyl fluorides are among the emerging fluorinated motifs. but are still quite underexplored. So, an efficient, fast, inexpensive, metal‐free and easy‐to‐perform method to access such compounds easily, even with sophisticated molecules, is described. The physicochemical properties of these compo...

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Veröffentlicht in:Chemistry : a European journal 2022-08, Vol.28 (43), p.n/a
Hauptverfasser: Bonnefoy, Clémence, Chefdeville, Emmanuel, Tourvieille, Christian, Panossian, Armen, Hanquet, Gilles, Leroux, Frédéric, Toulgoat, Fabien, Billard, Thierry
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Sprache:eng
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Zusammenfassung:Carbamoyl fluorides are among the emerging fluorinated motifs. but are still quite underexplored. So, an efficient, fast, inexpensive, metal‐free and easy‐to‐perform method to access such compounds easily, even with sophisticated molecules, is described. The physicochemical properties of these compounds were measured to give an insight into the potential of carbamoyl fluorides—in particular, their stability under close‐to‐physiological conditions. Finally, a first application in radiochemistry to obtain fluorine‐18 radiolabeled compounds easily is proposed. More information can be found in the Research Article by F. Toulgoat, T. Billard, and co‐workers (DOI: 10.1002/chem.202201589).
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.202202043