Cover Feature: Diarylcuprates for Selective Syntheses of Multifunctionalized Ketones from Thioesters under Mild Conditions (Chem. Eur. J. 26/2022)

The synthesis of ketone as a synthetic intermediate of canagliflozin from a gluconolactone‐derived thioester and a Grignard reagent with the aid of copper is likened to making Taiyaki, a Japanese fish‐shaped waffle with sweet red bean inside. The thioester (sweet red beans) and the Grignard reagent (waffle batter) are baked on a copper waffle iron to get the desired ketone as Taiyaki. More information can be found in the Research Article by H. Tsurugi, M. Seki, K. Mashima, and co‐workers (DOI: 10.1002/chem.202200474).