Electrochemical Synthesis of 3‐Bromoimidazo[1,2‐a]pyridines Directly from 2‐Aminopyridines and alpha‐Bromoketones

A highly efficient co‐electrolysis of 3‐bromoimidazo[1,2‐a]pyridines has been developed in a simple undivided cell without any external oxidant. This protocol proceeds smoothly to provide the products with a broad substrate scope through a domino condensation/bromination sequence. Importantly, it can be easily scaled up. To scale: An efficient approach for the synthesis of 3‐bromoimidazo[1,2‐a]pyridines from 2‐aminopyridines and α‐bromoketones is developed. This protocol provides products with a broad substrate scope under ambient conditions and in the absence of any chemical oxidant. Importantly, it can be easily scaled up.