Mixing Analysis for a Fermentation Broth of the Fungus Beauveria bassiana under Different Hydrodynamic Conditions in a Bioreactor

The performances of radial‐axial flow (Rushton‐Maxflo impellers) and axial‐radial flow (Maxflo‐Rushton impellers) mixers in the laminar‐transitional flow regime were experimentally and numerically investigated with Newtonian and non‐Newtonian fluids. The rheological properties for a fermentation bro...

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Veröffentlicht in:Chemical engineering & technology 2012-11, Vol.35 (11), p.1954-1961
Hauptverfasser: Núñez-Ramírez, D. M., Valencia-López, J. J., Calderas, F., Solís-Soto, A., López-Miranda, J., Medrano-Roldán, H., Medina-Torres, L.
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Sprache:eng
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Zusammenfassung:The performances of radial‐axial flow (Rushton‐Maxflo impellers) and axial‐radial flow (Maxflo‐Rushton impellers) mixers in the laminar‐transitional flow regime were experimentally and numerically investigated with Newtonian and non‐Newtonian fluids. The rheological properties for a fermentation broth consisting of the fungus Beauveria bassiana were studied under different hydrodynamic conditions in these systems. The bioreactor was a continuous stirred‐tank reactor (CSTR), set at different stirring velocities. The rheology of the systems exhibited shear‐thinning behavior which was modeled with the power law model. The experimental hydrodynamics and configuration modes were compared and simulated with a model fluid system and by numerical criteria (computational fluid dynamics). The R‐M mode was found to be more efficient than the M‐R rotating mode in terms of energy and homogenization time. The results will help in the optimization of scale‐up production of these fungi. The hydrodynamics of the fungi system Beauveria bassiana has been experimentally evaluated for different conditions in a mixing tank with a two‐impeller configuration and Newtonian as well as non‐Newtonian model fluids. Numerical simulations are essential to understand and optimize these systems. The simulation of streamlines for a radial‐axial Rushton‐Maxflo impeller configuration is presented.
ISSN:0930-7516
1521-4125
DOI:10.1002/ceat.201200130