Cover Feature: The Chirality of Aggregated Yariv Reagents Correlates with Their AGP‐Binding Ability (ChemBioChem 6/2022)

The Yariv reagents are a class of tris‐azo dyes, some of which stain and precipitate arabinogalactan proteins (AGPs), plant cell wall proteoglycans. These dyes form supramolecular aggregates in solution. In this study, CD spectroscopy revealed that the aggregates exhibit helical chirality. Only thos...

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Veröffentlicht in:Chembiochem : a European journal of chemical biology 2022-03, Vol.23 (6), p.n/a
Hauptverfasser: Hoshing, Raghuraj, Leeber, Blaise W., Kuhn, Helene, Caianiello, David, Dale, Brandon, Saladino, Michael, Lusi, Robert, Palaychuk, Natalie, Weingarten, Sarah, Basu, Amit
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Sprache:eng
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Zusammenfassung:The Yariv reagents are a class of tris‐azo dyes, some of which stain and precipitate arabinogalactan proteins (AGPs), plant cell wall proteoglycans. These dyes form supramolecular aggregates in solution. In this study, CD spectroscopy revealed that the aggregates exhibit helical chirality. Only those aggregates with right‐handed helicity have a fertile interaction with AGP, while those with left‐handed helicity do not bind. Artwork credit: D. Caianiello and M. Bohne. More information can be found in the Research Article by A. Basu et al.
ISSN:1439-4227
1439-7633
DOI:10.1002/cbic.202100613