Cover Feature: Site‐Specific Antibody Fragment Conjugates for Reversible Staining in Fluorescence Microscopy (7/2021)

To get one step closer to making fluorescence microscopy as easy as filling out shapes in a children's coloring book, we have developed a novel strategy for generating DNA‐ and PNA‐based protein–oligonucleotide conjugates. We use a chemo‐enzymatic, click chemistry–based approach via the TubTag...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chembiochem : a European journal of chemical biology 2021-04, Vol.22 (7), p.1112-1112
Hauptverfasser: Schwach, Jonathan, Kolobynina, Ksenia, Brandstetter, Katharina, Gerlach, Marcus, Ochtrop, Philipp, Helma, Jonas, Hackenberger, Christian P. R., Harz, Hartmann, Cardoso, M. Cristina, Leonhardt, Heinrich, Stengl, Andreas
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:To get one step closer to making fluorescence microscopy as easy as filling out shapes in a children's coloring book, we have developed a novel strategy for generating DNA‐ and PNA‐based protein–oligonucleotide conjugates. We use a chemo‐enzymatic, click chemistry–based approach via the TubTag to generate our conjugates as depicted in the magnifying glass. Those proteins can readily be used to “paint” our cell for fluorescence microscopy. More information can be found in the communication by J. Schwach, A. Stengl et al. Cover design: J. Schwach.
ISSN:1439-4227
1439-7633
DOI:10.1002/cbic.202100115