Front Cover: An AZT Analog with Strongly Pairing Ethynylpyridone Nucleobase and Its Antiviral Activity against HSV1 (Chem. Biodiversity 1/2021)

Front Cover: An AZT Analog with Strongly Pairing Ethynylpyridone Nucleobase and Its Antiviral Activity against HSV1 (Chem. Biodiversity 1/2021)

Front Cover. A new C‐nucleoside with strongly pairing ethynylmethylpyridone base and 3'‐azido‐2',3'‐dideoxyribose sugar dubbed 'AZW' was described. The image shows the structure of AZW against a backdrop of AZT in dotted cloud representation. The new nucleoside shows inhibit...

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Veröffentlicht in:Chemistry & biodiversity 2021-01, Vol.18 (1), p.n/a
Hauptverfasser: Han, Jianyang, Funk, Christina, Eyberg, Juri, Bailer, Susanne, Richert, Clemens
Format: Artikel
Sprache:eng
Schlagworte:
antiviral agents
C-nucleosides
HSV1
nucleosides
phosphoramidates
polymerase inhibitors
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Zusammenfassung:Front Cover. A new C‐nucleoside with strongly pairing ethynylmethylpyridone base and 3'‐azido‐2',3'‐dideoxyribose sugar dubbed 'AZW' was described. The image shows the structure of AZW against a backdrop of AZT in dotted cloud representation. The new nucleoside shows inhibitory activity against Herpes simplex virus type 1 (HSV1) as reported by Richert et al. in their full paper at10.1002/cbdv.202000937.
ISSN:1612-1872
1612-1880
DOI:10.1002/cbdv.202001048