What goes on behind closed doors: physiological versus pharmacological steroid hormone actions

Steroid-hormone-activated receptor proteins are among the best-understood class of factors for altering gene transcription in cells. Steroid receptors are of major importance in maintaining normal human physiology by responding to circulating concentrations of steroid in the nM range. Nonetheless, m...

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Veröffentlicht in:	BioEssays 2008-08, Vol.30 (8), p.744-756
1. Verfasser:	Simons, S. Stoney Jr
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Nucleus - metabolism DNA - metabolism Dose-Response Relationship, Drug Gene Expression Regulation Glucocorticoids - metabolism Humans Kinetics Models, Biological Protein Processing, Post-Translational Receptors, Cytoplasmic and Nuclear - metabolism Receptors, Glucocorticoid - metabolism Receptors, Steroid - metabolism Steroids - metabolism Transcription, Genetic
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