Monozygotic twins discordant for systemic lupus erythematosus
A pair of monozygotic twins discordant for systemic lupus erythematosus (SLE) were studied and no differences noted in their immune response to tetanus toxoid, keyhole lympet hemocyanin, DNCB, delayed sensitivity, or antibody titers to viruses. Both were noted to have biologically false positive ser...
Gespeichert in:
| Veröffentlicht in: | Arthritis and rheumatism 1975-05, Vol.18 (3), p.193-200 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 200 |
|---|---|
| container_issue | 3 |
| container_start_page | 193 |
| container_title | Arthritis and rheumatism |
| container_volume | 18 |
| creator | Yocum, Michael W. Grossman, Jay Waterhouse, Christine Abraham, George N. May‐June, Allyn G. Condemi, John J. |
| description | A pair of monozygotic twins discordant for systemic lupus erythematosus (SLE) were studied and no differences noted in their immune response to tetanus toxoid, keyhole lympet hemocyanin, DNCB, delayed sensitivity, or antibody titers to viruses. Both were noted to have biologically false positive serology at an early age, but only one twin developed SLE. The clinically unaffected twin underwent castration at an early age, suggesting that ovarian hormones May‐June play an important role in the development of SLE. |
| doi_str_mv | 10.1002/art.1780180301 |
| format | Article |
| fullrecord | <record><control><sourceid>wiley_cross</sourceid><recordid>TN_cdi_crossref_primary_10_1002_art_1780180301</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>ART1780180301</sourcerecordid><originalsourceid>FETCH-LOGICAL-c2221-b6c276ac97d7ab26e0fd39787ea9688ab3467f3ebb50bfc9dfbd7587c67089523</originalsourceid><addsrcrecordid>eNqFkE1LAzEQhoNYtFavXrzsH9g6SZpNcvBQil9QEaSel3zqSrcpSZay_npXK-rN0zA88z4wL0LnGKYYgFyqmKeYC8ACKOADNMaMyBIwxYdoDACzkjKJj9FJSm_DSiijR2g0k1iwMbp6CJvw3r-E3Jgi75pNKmyTTIhWbXLhQyxSn7JrB7rutl0qXOzzq2tVDqlLp2jk1Tq5s-85Qc8316vFXbl8vL1fzJelIYTgUleG8EoZyS1XmlQOvKWSC-6UrIRQms4q7qnTmoH2RlqvLWeCm4qDkIzQCZruvSaGlKLz9TY2rYp9jaH-LKEeSqh_SxgCF_vAttOtsz_nX18PVO7prlm7_h9XPX9a_TF_AFIkabI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Monozygotic twins discordant for systemic lupus erythematosus</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><source>Alma/SFX Local Collection</source><creator>Yocum, Michael W. ; Grossman, Jay ; Waterhouse, Christine ; Abraham, George N. ; May‐June, Allyn G. ; Condemi, John J.</creator><creatorcontrib>Yocum, Michael W. ; Grossman, Jay ; Waterhouse, Christine ; Abraham, George N. ; May‐June, Allyn G. ; Condemi, John J.</creatorcontrib><description>A pair of monozygotic twins discordant for systemic lupus erythematosus (SLE) were studied and no differences noted in their immune response to tetanus toxoid, keyhole lympet hemocyanin, DNCB, delayed sensitivity, or antibody titers to viruses. Both were noted to have biologically false positive serology at an early age, but only one twin developed SLE. The clinically unaffected twin underwent castration at an early age, suggesting that ovarian hormones May‐June play an important role in the development of SLE.</description><identifier>ISSN: 0004-3591</identifier><identifier>EISSN: 1529-0131</identifier><identifier>DOI: 10.1002/art.1780180301</identifier><identifier>PMID: 49185</identifier><language>eng</language><publisher>New York: John Wiley & Sons, Inc</publisher><subject>Adult ; Antibodies, Viral - analysis ; Antigen-Antibody Reactions ; Antigens, Viral ; Autoantibodies ; Castration ; Diseases in Twins ; Female ; gamma-Globulins - metabolism ; Hemagglutination Tests ; Hemocyanins - immunology ; Humans ; Hypersensitivity, Delayed ; Immunoglobulin Fragments - metabolism ; Immunoglobulin kappa-Chains - metabolism ; Immunoglobulin lambda-Chains - metabolism ; Lupus Erythematosus, Systemic - etiology ; Lymphocytes - immunology ; Pregnancy ; Tetanus Toxoid ; Twins, Monozygotic</subject><ispartof>Arthritis and rheumatism, 1975-05, Vol.18 (3), p.193-200</ispartof><rights>Copyright © 1975 American College of Rheumatology</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c2221-b6c276ac97d7ab26e0fd39787ea9688ab3467f3ebb50bfc9dfbd7587c67089523</citedby><cites>FETCH-LOGICAL-c2221-b6c276ac97d7ab26e0fd39787ea9688ab3467f3ebb50bfc9dfbd7587c67089523</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fart.1780180301$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fart.1780180301$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/49185$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yocum, Michael W.</creatorcontrib><creatorcontrib>Grossman, Jay</creatorcontrib><creatorcontrib>Waterhouse, Christine</creatorcontrib><creatorcontrib>Abraham, George N.</creatorcontrib><creatorcontrib>May‐June, Allyn G.</creatorcontrib><creatorcontrib>Condemi, John J.</creatorcontrib><title>Monozygotic twins discordant for systemic lupus erythematosus</title><title>Arthritis and rheumatism</title><addtitle>Arthritis Rheum</addtitle><description>A pair of monozygotic twins discordant for systemic lupus erythematosus (SLE) were studied and no differences noted in their immune response to tetanus toxoid, keyhole lympet hemocyanin, DNCB, delayed sensitivity, or antibody titers to viruses. Both were noted to have biologically false positive serology at an early age, but only one twin developed SLE. The clinically unaffected twin underwent castration at an early age, suggesting that ovarian hormones May‐June play an important role in the development of SLE.</description><subject>Adult</subject><subject>Antibodies, Viral - analysis</subject><subject>Antigen-Antibody Reactions</subject><subject>Antigens, Viral</subject><subject>Autoantibodies</subject><subject>Castration</subject><subject>Diseases in Twins</subject><subject>Female</subject><subject>gamma-Globulins - metabolism</subject><subject>Hemagglutination Tests</subject><subject>Hemocyanins - immunology</subject><subject>Humans</subject><subject>Hypersensitivity, Delayed</subject><subject>Immunoglobulin Fragments - metabolism</subject><subject>Immunoglobulin kappa-Chains - metabolism</subject><subject>Immunoglobulin lambda-Chains - metabolism</subject><subject>Lupus Erythematosus, Systemic - etiology</subject><subject>Lymphocytes - immunology</subject><subject>Pregnancy</subject><subject>Tetanus Toxoid</subject><subject>Twins, Monozygotic</subject><issn>0004-3591</issn><issn>1529-0131</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1975</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LAzEQhoNYtFavXrzsH9g6SZpNcvBQil9QEaSel3zqSrcpSZay_npXK-rN0zA88z4wL0LnGKYYgFyqmKeYC8ACKOADNMaMyBIwxYdoDACzkjKJj9FJSm_DSiijR2g0k1iwMbp6CJvw3r-E3Jgi75pNKmyTTIhWbXLhQyxSn7JrB7rutl0qXOzzq2tVDqlLp2jk1Tq5s-85Qc8316vFXbl8vL1fzJelIYTgUleG8EoZyS1XmlQOvKWSC-6UrIRQms4q7qnTmoH2RlqvLWeCm4qDkIzQCZruvSaGlKLz9TY2rYp9jaH-LKEeSqh_SxgCF_vAttOtsz_nX18PVO7prlm7_h9XPX9a_TF_AFIkabI</recordid><startdate>197505</startdate><enddate>197505</enddate><creator>Yocum, Michael W.</creator><creator>Grossman, Jay</creator><creator>Waterhouse, Christine</creator><creator>Abraham, George N.</creator><creator>May‐June, Allyn G.</creator><creator>Condemi, John J.</creator><general>John Wiley & Sons, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>197505</creationdate><title>Monozygotic twins discordant for systemic lupus erythematosus</title><author>Yocum, Michael W. ; Grossman, Jay ; Waterhouse, Christine ; Abraham, George N. ; May‐June, Allyn G. ; Condemi, John J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c2221-b6c276ac97d7ab26e0fd39787ea9688ab3467f3ebb50bfc9dfbd7587c67089523</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1975</creationdate><topic>Adult</topic><topic>Antibodies, Viral - analysis</topic><topic>Antigen-Antibody Reactions</topic><topic>Antigens, Viral</topic><topic>Autoantibodies</topic><topic>Castration</topic><topic>Diseases in Twins</topic><topic>Female</topic><topic>gamma-Globulins - metabolism</topic><topic>Hemagglutination Tests</topic><topic>Hemocyanins - immunology</topic><topic>Humans</topic><topic>Hypersensitivity, Delayed</topic><topic>Immunoglobulin Fragments - metabolism</topic><topic>Immunoglobulin kappa-Chains - metabolism</topic><topic>Immunoglobulin lambda-Chains - metabolism</topic><topic>Lupus Erythematosus, Systemic - etiology</topic><topic>Lymphocytes - immunology</topic><topic>Pregnancy</topic><topic>Tetanus Toxoid</topic><topic>Twins, Monozygotic</topic><toplevel>online_resources</toplevel><creatorcontrib>Yocum, Michael W.</creatorcontrib><creatorcontrib>Grossman, Jay</creatorcontrib><creatorcontrib>Waterhouse, Christine</creatorcontrib><creatorcontrib>Abraham, George N.</creatorcontrib><creatorcontrib>May‐June, Allyn G.</creatorcontrib><creatorcontrib>Condemi, John J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Arthritis and rheumatism</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yocum, Michael W.</au><au>Grossman, Jay</au><au>Waterhouse, Christine</au><au>Abraham, George N.</au><au>May‐June, Allyn G.</au><au>Condemi, John J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Monozygotic twins discordant for systemic lupus erythematosus</atitle><jtitle>Arthritis and rheumatism</jtitle><addtitle>Arthritis Rheum</addtitle><date>1975-05</date><risdate>1975</risdate><volume>18</volume><issue>3</issue><spage>193</spage><epage>200</epage><pages>193-200</pages><issn>0004-3591</issn><eissn>1529-0131</eissn><abstract>A pair of monozygotic twins discordant for systemic lupus erythematosus (SLE) were studied and no differences noted in their immune response to tetanus toxoid, keyhole lympet hemocyanin, DNCB, delayed sensitivity, or antibody titers to viruses. Both were noted to have biologically false positive serology at an early age, but only one twin developed SLE. The clinically unaffected twin underwent castration at an early age, suggesting that ovarian hormones May‐June play an important role in the development of SLE.</abstract><cop>New York</cop><pub>John Wiley & Sons, Inc</pub><pmid>49185</pmid><doi>10.1002/art.1780180301</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0004-3591 |
| ispartof | Arthritis and rheumatism, 1975-05, Vol.18 (3), p.193-200 |
| issn | 0004-3591 1529-0131 |
| language | eng |
| recordid | cdi_crossref_primary_10_1002_art_1780180301 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection |
| subjects | Adult Antibodies, Viral - analysis Antigen-Antibody Reactions Antigens, Viral Autoantibodies Castration Diseases in Twins Female gamma-Globulins - metabolism Hemagglutination Tests Hemocyanins - immunology Humans Hypersensitivity, Delayed Immunoglobulin Fragments - metabolism Immunoglobulin kappa-Chains - metabolism Immunoglobulin lambda-Chains - metabolism Lupus Erythematosus, Systemic - etiology Lymphocytes - immunology Pregnancy Tetanus Toxoid Twins, Monozygotic |
| title | Monozygotic twins discordant for systemic lupus erythematosus |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-24T22%3A40%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-wiley_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Monozygotic%20twins%20discordant%20for%20systemic%20lupus%20erythematosus&rft.jtitle=Arthritis%20and%20rheumatism&rft.au=Yocum,%20Michael%20W.&rft.date=1975-05&rft.volume=18&rft.issue=3&rft.spage=193&rft.epage=200&rft.pages=193-200&rft.issn=0004-3591&rft.eissn=1529-0131&rft_id=info:doi/10.1002/art.1780180301&rft_dat=%3Cwiley_cross%3EART1780180301%3C/wiley_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/49185&rfr_iscdi=true |