Cover Picture: Conditional Singlet Oxygen Generation through a Bioorthogonal DNA‐targeted Tetrazine Reaction (Angew. Chem. Int. Ed. 37/2019)

Cover Picture: Conditional Singlet Oxygen Generation through a Bioorthogonal DNA‐targeted Tetrazine Reaction (Angew. Chem. Int. Ed. 37/2019)

Tetrazine can act as an effective singlet oxygen quencher of halogenated BODIPY photosensitizers. In their Communication on page 12868 ff., O. Vázquez and co‐workers report bioorthogonal, activatable probes that allow both organelle‐specific localization and conditional singlet oxygen production sim...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Angewandte Chemie International Edition 2019-09, Vol.58 (37), p.12719-12719
Hauptverfasser: Linden, Greta, Zhang, Lei, Pieck, Fabian, Linne, Uwe, Kosenkov, Dmitri, Tonner, Ralf, Vázquez, Olalla
Format: Artikel
Sprache:eng
Schlagworte:
bioorthogonal reactions
BODIPY dyes
photodynamic therapy
singlet oxygen
tetrazine
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Tetrazine can act as an effective singlet oxygen quencher of halogenated BODIPY photosensitizers. In their Communication on page 12868 ff., O. Vázquez and co‐workers report bioorthogonal, activatable probes that allow both organelle‐specific localization and conditional singlet oxygen production simultaneously. These compounds open new avenues to combat the current limitations of photodynamic therapy. Cover design: Prof. M. Eugenio Vázquez.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201909198