Inside Cover: Molecularly Imprinted Nanogels Acquire Stealth In Situ by Cloaking Themselves with Native Dysopsonic Proteins (Angew. Chem. Int. Ed. 25/2017)

Cloaking nanogels with albumin yields stealth nanocarriers. In their Communication on page 7088 ff., T. Takeuchi and co‐workers describe the regulation of protein corona formation by molecular imprinting of polymeric nanogels. The nanogels acquire stealth in situ by capturing albumin after intraveno...

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Veröffentlicht in:Angewandte Chemie International Edition 2017-06, Vol.56 (25), p.7006-7006
Hauptverfasser: Takeuchi, Toshifumi, Kitayama, Yukiya, Sasao, Reo, Yamada, Takuya, Toh, Kazuko, Matsumoto, Yu, Kataoka, Kazunori
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Sprache:eng
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Zusammenfassung:Cloaking nanogels with albumin yields stealth nanocarriers. In their Communication on page 7088 ff., T. Takeuchi and co‐workers describe the regulation of protein corona formation by molecular imprinting of polymeric nanogels. The nanogels acquire stealth in situ by capturing albumin after intravenous injection, forming an albumin‐rich corona. As the nanogels accumulate passively in tumor tissue, this strategy may influence the development of drug nanocarriers for cancer therapy.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201704551