Efficient Aryl-(Hetero)Aryl Coupling by Activation of CCl and CF Bonds Using Nickel Complexes of Air-Stable Phosphine Oxides

A couple of couplings: Air‐stable diamino‐ and dioxophosphine oxides are used as preligands in the nickel‐catalyzed Kumada cross‐coupling reactions of aryl Grignard reagents. A sterically hindered preligand allows for highly efficient cross‐coupling of aryl fluorides at ambient temperature (acac=ace...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Angewandte Chemie International Edition 2005-11, Vol.44 (44), p.7216-7219
Hauptverfasser:	Ackermann, Lutz, Born, Robert, Spatz, Julia H., Meyer, Daniel
Format:	Artikel
Sprache:	eng
Schlagworte:	Air Carbon - chemistry Chlorine - chemistry CC coupling CF activation Fluorine - chemistry Grignard reaction Molecular Structure nickel Nickel - chemistry Organometallic Compounds - chemistry Oxides - chemistry phosphine oxides Phosphines - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A couple of couplings: Air‐stable diamino‐ and dioxophosphine oxides are used as preligands in the nickel‐catalyzed Kumada cross‐coupling reactions of aryl Grignard reagents. A sterically hindered preligand allows for highly efficient cross‐coupling of aryl fluorides at ambient temperature (acac=acetylacetonate).
ISSN:	1433-7851 1521-3773
DOI:	10.1002/anie.200501860