Cover Picture: Efficient Asymmetric Hydrogenation of Pyridines (Angew. Chem. Int. Ed. 21/2004)

The stereoselective hydrogenation of oxazolidinone‐substituted pyridines shown in the cover picture gives piperidines containing up to four new stereocenters. One of the biologically active compounds readily accessible by this method is (S)‐coniine, the poisonous hemlock alkaloid used in ancient Gre...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Angewandte Chemie International Edition 2004-05, Vol.43 (21), p.2727-2727
Hauptverfasser: Glorius, Frank, Spielkamp, Nick, Holle, Sigrid, Goddard, Richard, Lehmann, Christian W.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The stereoselective hydrogenation of oxazolidinone‐substituted pyridines shown in the cover picture gives piperidines containing up to four new stereocenters. One of the biologically active compounds readily accessible by this method is (S)‐coniine, the poisonous hemlock alkaloid used in ancient Greece for executions. The famous painting by David shows Socrates shortly before drinking from the poison chalice. F. Glorius et al. describe this synthetic method on pages 2850 ff.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200490062