Synthesis and Enzymatic Degradation of Dendrimers from (R)-3-Hydroxybutanoic Acid and Trimesic Acid

Synthesis and Enzymatic Degradation of Dendrimers from (R)-3-Hydroxybutanoic Acid and Trimesic Acid

Monodisperse, chiral dendrimers from trimesic acid and (R)‐3‐hydroxybutanoic acid were synthesized and characterized. Preliminary investigations have shown that these biodegradable dendrimers (depicted on the right) are substrates for hydrolases.

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Veröffentlicht in:Angewandte Chemie International Edition 1996-12, Vol.35 (23-24), p.2795-2797
Hauptverfasser: Seebach, Dieter, Herrmann, Guido F., Lengweiler, Urs D., Bachmann, Beat M., Amrein, Walter
Format: Artikel
Sprache:eng
Schlagworte:
biodegradability
chirality
dendrimers
enzymes
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Beschreibung
Zusammenfassung:Monodisperse, chiral dendrimers from trimesic acid and (R)‐3‐hydroxybutanoic acid were synthesized and characterized. Preliminary investigations have shown that these biodegradable dendrimers (depicted on the right) are substrates for hydrolases.
ISSN:0570-0833
1521-3773
DOI:10.1002/anie.199627951