Increased Selectivity of a Simple Photosensitive Probe in the Presence of Large Proportions of Cholesterol

Increased Selectivity of a Simple Photosensitive Probe in the Presence of Large Proportions of Cholesterol

The “half‐probe” molecule 1, when a constituent of phospholipid vesicles in the presence of cholesterol in large, but biologically reasonable proportions (over 30 mol%), selectively attacks the middle of the bilayer.

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Veröffentlicht in:Angewandte Chemie (International ed.) 1994-06, Vol.33 (11), p.1176-1178
Hauptverfasser: Fredriksen, Siw Bodil, Dollé, Valérie, Yamamoto, Masakuni, Nakatani, Yoichi, Goeldner, Maurice, Ourisson, Guy
Format: Artikel
Sprache:eng
Schlagworte:
Chemistry
Colloidal state and disperse state
Exact sciences and technology
General and physical chemistry
Membranes
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Beschreibung
Zusammenfassung:The “half‐probe” molecule 1, when a constituent of phospholipid vesicles in the presence of cholesterol in large, but biologically reasonable proportions (over 30 mol%), selectively attacks the middle of the bilayer.
ISSN:0570-0833
1521-3773
DOI:10.1002/anie.199411761