S-Glycosylated Cyclic Peptides

S-Glycosylated Cyclic Peptides

The high chemical and enzymatic stability of thioglycosides stimulated the synthesis of S‐glycosylated cyclopeptides. The structural properties of this new class of compounds were established by conformational analysis with 2D NMR methods and molecular dynamics calculations. These substances are of...

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Veröffentlicht in:Angewandte Chemie (International ed.) 1993-02, Vol.32 (2), p.269-271
Hauptverfasser: Gerz, Manfred, Matter, Hans, Kessler, Horst
Format: Artikel
Sprache:eng
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Chemistry
Exact sciences and technology
Organic chemistry
Peptides
Preparations and properties
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container_start_page 269
container_title Angewandte Chemie (International ed.)
container_volume 32
creator Gerz, Manfred
Matter, Hans
Kessler, Horst
description The high chemical and enzymatic stability of thioglycosides stimulated the synthesis of S‐glycosylated cyclopeptides. The structural properties of this new class of compounds were established by conformational analysis with 2D NMR methods and molecular dynamics calculations. These substances are of interest for the development of site‐specific drugs.
doi_str_mv 10.1002/anie.199302691
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ispartof Angewandte Chemie (International ed.), 1993-02, Vol.32 (2), p.269-271
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language eng
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source Wiley Online Library Journals Frontfile Complete
subjects Chemistry
Exact sciences and technology
Organic chemistry
Peptides
Preparations and properties
title S-Glycosylated Cyclic Peptides
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