S-Glycosylated Cyclic Peptides

The high chemical and enzymatic stability of thioglycosides stimulated the synthesis of S‐glycosylated cyclopeptides. The structural properties of this new class of compounds were established by conformational analysis with 2D NMR methods and molecular dynamics calculations. These substances are of...

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Veröffentlicht in:	Angewandte Chemie (International ed.) 1993-02, Vol.32 (2), p.269-271
Hauptverfasser:	Gerz, Manfred, Matter, Hans, Kessler, Horst
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Exact sciences and technology Organic chemistry Peptides Preparations and properties
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	The high chemical and enzymatic stability of thioglycosides stimulated the synthesis of S‐glycosylated cyclopeptides. The structural properties of this new class of compounds were established by conformational analysis with 2D NMR methods and molecular dynamics calculations. These substances are of interest for the development of site‐specific drugs.
ISSN:	0570-0833 1521-3773
DOI:	10.1002/anie.199302691