Oxidative Fluorination of Arenes

Fluorophenols such as 3 with interesting substitution patterns can be obtained by oxidation of the phenols 1 in an HF/base mixture to 2 and then further reaction with nucleophiles. HF/base mixtures can also be used for the electrochemical oxidative fluorination of benzene‐like arenes.

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Veröffentlicht in:Angewandte Chemie International Edition 1989-07, Vol.28 (7), p.927-928
Hauptverfasser: Meurs, Jan H. H., Sopher, David W., Eilenberg, Wolf
Format: Artikel
Sprache:eng
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Zusammenfassung:Fluorophenols such as 3 with interesting substitution patterns can be obtained by oxidation of the phenols 1 in an HF/base mixture to 2 and then further reaction with nucleophiles. HF/base mixtures can also be used for the electrochemical oxidative fluorination of benzene‐like arenes.
ISSN:0570-0833
1521-3773
DOI:10.1002/anie.198909271