Edrophonium: An aid in the diagnosis of acute organophosphate poisoning

Unsuspected accidental cutaneous exposure to an organophosphate insecticide caused flaccid paralysis in a 10‐year‐old girl. Electromyogram demonstrated repetitive compound muscle action potentials in response to a single stimulus of nerve; decremental response, more prominent at higher rates of stim...

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Veröffentlicht in:	Annals of neurology 1986-05, Vol.19 (5), p.508-510
Hauptverfasser:	Maselli, Ricardo, Jacobsen, John H., Spire, Jean-Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials Acute Disease Applied sciences Biological and medical sciences Child Edrophonium Electromyography Exact sciences and technology Female Humans Medical sciences Methyl Parathion - poisoning Other techniques and industries Parathion - analogs & derivatives Pesticides, fertilizers and other agrochemicals toxicology Toxicology
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Zusammenfassung:	Unsuspected accidental cutaneous exposure to an organophosphate insecticide caused flaccid paralysis in a 10‐year‐old girl. Electromyogram demonstrated repetitive compound muscle action potentials in response to a single stimulus of nerve; decremental response, more prominent at higher rates of stimulation; worsening of decremental response after edrophonium injection; and normal nerve conduction velocities. Electromyogram with repetitive nerve stimulation and an edrophonium test may provide a simple and rapid method for diagnosis of acute organophosphate poisoning.
ISSN:	0364-5134 1531-8249
DOI:	10.1002/ana.410190517