Imparied biotin status in anticonvulsant therapy
In 264 epileptics undergoing long‐term therapy with anticonvulsants, significantly reduced plasma biotin levels were found compared with a normal control group: 74% of the epileptics had biotin levels for those treated with sodium valproate were higher than for those treated with phenytion, primidon...
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| Veröffentlicht in: | Annals of neurology 1982-11, Vol.12 (5), p.485-486 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | In 264 epileptics undergoing long‐term therapy with anticonvulsants, significantly reduced plasma biotin levels were found compared with a normal control group: 74% of the epileptics had biotin levels for those treated with sodium valproate were higher than for those treated with phenytion, primidone, or carbamazepine. The observed reduction in biotin levels might be a factor influencing the efficacy of these three antionvulsants. |
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| ISSN: | 0364-5134 1531-8249 |
| DOI: | 10.1002/ana.410120513 |