Precision medicine in chronic disease management: The multiple sclerosis B io S creen

We present a precision medicine application developed for multiple sclerosis (MS): the MS BioScreen. This new tool addresses the challenges of dynamic management of a complex chronic disease; the interaction of clinicians and patients with such a tool illustrates the extent to which translational di...

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Veröffentlicht in:Annals of neurology 2014-11, Vol.76 (5), p.633-642
Hauptverfasser: Gourraud, Pierre‐Antoine, Henry, Roland G., Cree, Bruce A. C., Crane, Jason C., Lizee, Antoine, Olson, Marram P., Santaniello, Adam V., Datta, Esha, Zhu, Alyssa H., Bevan, Carolyn J., Gelfand, Jeffrey M., Graves, Jennifer S., Goodin, Douglas S., Green, Ari J., von Büdingen, H.‐Christian, Waubant, Emmanuelle, Zamvil, Scott S., Crabtree‐Hartman, Elizabeth, Nelson, Sarah, Baranzini, Sergio E., Hauser, Stephen L.
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Sprache:eng
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Zusammenfassung:We present a precision medicine application developed for multiple sclerosis (MS): the MS BioScreen. This new tool addresses the challenges of dynamic management of a complex chronic disease; the interaction of clinicians and patients with such a tool illustrates the extent to which translational digital medicine—that is, the application of information technology to medicine—has the potential to radically transform medical practice. We introduce 3 key evolutionary phases in displaying data to health care providers, patients, and researchers: visualization (accessing data), contextualization (understanding the data), and actionable interpretation (real‐time use of the data to assist decision making). Together, these form the stepping stones that are expected to accelerate standardization of data across platforms, promote evidence‐based medicine, support shared decision making, and ultimately lead to improved outcomes. Ann Neurol 2014;76:633–642
ISSN:0364-5134
1531-8249
DOI:10.1002/ana.24282