Correlation between heartrate and alpha Event‐Related Desynchronization during a Stroop task helps reveal cognitively healthy individuals with pathological CSF amyloid/tau

Background Alzheimer’s Disease (AD) impacts brain regions associated with memory and executive function in early stages. The Stroop task is used to evaluate inhibition, a common factor for executive functioning. Alpha Event‐Related Desynchronization (ERD) from electroencephalogram (EEG) analysis eva...

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Veröffentlicht in:Alzheimer's & dementia 2023-12, Vol.19 (S15), p.n/a
Hauptverfasser: Molloy, Cathleen, Choy, Elizabeth Hok Yee, Al‐Ezzi, Abdulhakim Abdullah A, Buennagel, David P, Aguda, Shelly, Nolty, Anne, Spezzaferri, Mitchell, Sin, Caleb, Rising, Shant, Fonteh, Alfred N., Minazad, Yafa, Kleinman, Michael T., Kloner, Robert A, Arakaki, Xianghong
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Sprache:eng
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Zusammenfassung:Background Alzheimer’s Disease (AD) impacts brain regions associated with memory and executive function in early stages. The Stroop task is used to evaluate inhibition, a common factor for executive functioning. Alpha Event‐Related Desynchronization (ERD) from electroencephalogram (EEG) analysis evaluates brain activation during a task. Also of interest is cardiovascular function such as heart rate (HR) and blood pressure (BP) as it relates to cognitive functioning in AD progression. However, the combined analysis of functional EEG with HR and BP have not been thoroughly reported in a Cognitively Healthy (CH) cohort. To fill this gap, we studied these measurements in CH participants who underwent a Stroop task. Method We previously reported Stroop alpha ERD of CH participants when their cerebrospinal fluid amyloid/tau ratio were normal (≥2.71, CH‐NATs) or pathological (
ISSN:1552-5260
1552-5279
DOI:10.1002/alz.076218