Deficits in mitochondrial function and glucose metabolism seen in sporadic and familial Alzheimer’s disease derived Astrocytes are ameliorated by increasing hexokinase 1

Background Astrocytes have multiple roles including providing neurons with metabolic substrates and maintaining neurotransmitters at neuronal synapses. Astrocyte glucose metabolism plays a key role in learning and memory with astrocytic glycogen a key substrate supporting memory encoding. The homeos...

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Veröffentlicht in:	Alzheimer's & dementia 2023-12, Vol.19 (S13), p.n/a
Hauptverfasser:	Bell, Simon M, Wareing, Hollie, Hamshaw, Alexander, De, Suman, New, Elizabeth, Shaw, Pamela, De Marco, Matteo, Venneri, Annalena, Blackburn, Daniel J, Ferraiuolo, Laura, Mortiboys, Heather
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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