DNA methylation profiling of individual neurons isolated from post‐mortem brain tissue using laser capture microdissection and adapted limiting dilution bisulfite pyrosequencing

Background A challenge frequently encountered in neuroepigenomic research, especially in the context of neurodegenerative diseases such as Alzheimer’s disease, is the difficulty of measuring epigenetic patterns in heterogenous bulk tissue samples, as these are known to cause noise during profiling....

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Veröffentlicht in:Alzheimer's & dementia 2023-12, Vol.19 (S12), p.n/a
Hauptverfasser: Riemens, Renzo J.M., Kenis, Gunter, Nolz, Jennifer, Chaves, Sonia C. Susano, Duroux, Diane, Pishva, Ehsan, Mastroeni, Diego, Van Steen, Kristel, Haaf, Thomas, Hove, Daniel L. A.
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Sprache:eng
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