Ligand‐Free Zn Catalyzed Synthesis of Functionalized Indoloacridines
An efficient, ligand‐free, and Zn‐catalyzed dehydrogenation of acridinol/ cyclization of imine product/ dehydrogenative C(sp 3 )‐H functionalization utilizing ChCl‐based deep eutectic solvent system for the assembly of functionalized indoloacridines 9 is reported. The protocol features mild reaction...
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| Veröffentlicht in: | Asian journal of organic chemistry 2024-11 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | An efficient, ligand‐free, and Zn‐catalyzed dehydrogenation of acridinol/ cyclization of imine product/ dehydrogenative C(sp 3 )‐H functionalization utilizing ChCl‐based deep eutectic solvent system for the assembly of functionalized indoloacridines 9 is reported. The protocol features mild reaction conditions, VOCs free process, broad substrate scope, and applicable gram‐scale synthesis. Furthermore, absorption and solvatochromism properties were explored for the synthesized compounds. |
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| ISSN: | 2193-5807 2193-5815 |
| DOI: | 10.1002/ajoc.202400482 |