Regioselective Synthesis of Thiocyanate‐Containing Isoxazolines via Fe III /K 2 S 2 O 8 ‐Mediated Radical Thiocyanation/Cyclization Cascade Reaction of β,γ‐Unsaturated Oximes

A simple approach for the synthesis of thiocyanate‐containing isoxazolines by Fe III /K 2 S 2 O 8 mediated radical thiocyanation/cyclization cascade reaction of accessible β,γ‐unsaturated oximes has been developed. The high selectivity, mild reaction conditions and absence of harmful heavy‐metal reagents render this reaction attractive. Additionally, the thiocyanate group from isoxazolines could be easily converted to various important functional groups, which could make these compounds important building blocks in organic synthesis.