Front Cover Picture: Site-Selective Iron(III) Chloride-Catalyzed Arylation of 4-Aryl-4-methoxy-2,5-cyclohexadienones for the Synthesis of Polyarylated Phenols (Adv. Synth. Catal. 23/2016)

The front cover picture, provided by Masahiro Masuda, Chie Morishige, Yoshinari Sawama, Hironao Sajiki and co‐workers, illustrates the stepwise modification of 4‐arylphenols into meta‐terphenyls and 2,4,6‐triarylphenols. Iodine oxidation of 4‐arylphenols in methanol gives 4‐aryl‐4‐methoxy‐2,5‐cyclohexadienones, which undergo site‐selective FeCl3‐catalyzed Friedel–Crafts arylation to provide meta‐terphenyls. The consecutive iodine oxidation of meta‐terphenyls and iron‐catalyzed arylation give 2,4,6‐triarylphenols. The use of a different arene in each step can provide highly‐functionalized and materially‐useful polyarenes. Details can be found in the communication on pages 3683–3687 (Y. Sawama, M. Masuda, R. Nakatani, H. Yokoyama, Y. Monguchi, T. Dohi, Y. Kita, H. Sajiki, Adv. Synth. Catal. 2016, 358, 3683–3687; DOI: 10.1002/adsc.201600577).