Photoacoustic Imaging: An IR820 Dye–Protein Complex for Second Near‐Infrared Window and Photoacoustic Imaging (Advanced Optical Materials 4/2020)

After mixing a sulfonated NIR‐I organic dye (IR820) with human serum albumin (HAS), fluorescence in the biological NIR‐II window of the IR820–HSA organic complex increases dramatically, as shown by Yaming Li, Zhen Cheng and co‐workers in article number 1901471. In vivo NIR‐II imaging with IR820–HSA can noninvasively and dynamically be used to visualize and monitor the physiological and pathological conditions of the vascular system, lymphatic drainage system, and tumor‐bearing mice, as well as allow image‐guided tumor resection.