Lipid Deposition Profiles Influence Foreign Body Responses (Adv. Mater. 21/2023)

Biomaterials In article number 2205709, Christian C. Schreib, Omid Veiseh, and co‐workers explore how lipid deposition affects the way the body responds to implanted biomaterials. They discover that certain types of phospholipids tend to accumulate on immune‐evasive implants, while different sets of...

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Veröffentlicht in:	Advanced materials (Weinheim) 2023-05, Vol.35 (21), p.n/a
Hauptverfasser:	Schreib, Christian C., Jarvis, Maria I., Terlier, Tanguy, Goell, Jacob, Mukherjee, Sudip, Doerfert, Michael D., Wilson, Taylor Anne, Beauregard, Michael, Martins, Kevin N., Lee, Jared, Sanchez Solis, Leonardo D., Vazquez, Esperanza, Oberli, Matthias A., Hanak, Brian W., Diehl, Michael, Hilton, Isaac, Veiseh, Omid
Format:	Artikel
Sprache:	eng
Schlagworte:	biomaterials foreign body responses immune responses lipids medical devices surface analyses tof‐sims
Online-Zugang:	Volltext
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Zusammenfassung:	Biomaterials In article number 2205709, Christian C. Schreib, Omid Veiseh, and co‐workers explore how lipid deposition affects the way the body responds to implanted biomaterials. They discover that certain types of phospholipids tend to accumulate on immune‐evasive implants, while different sets of fatty acid lipids deposit on immunogenic implants. These lipids directly impact the transcriptome of macrophages found on the surface of the implant materials.
ISSN:	0935-9648 1521-4095
DOI:	10.1002/adma.202370150