Tumor Microenvironments: Rapid 3D Extrusion of Synthetic Tumor Microenvironments (Adv. Mater. 37/2015)

The generation of cell‐laden spatially organized 3D hydrogels is demonstrated by K. A. Kilian and co‐workers on page 5512, using macrophages and breast adenocarcinoma cells as a heterotypic model that mimics aspects of the tumor microenvironment. This versatile and tunable approach for fabricating s...

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Veröffentlicht in:Advanced materials (Weinheim) 2015-10, Vol.27 (37), p.5445-5445
Hauptverfasser: Grolman, Joshua M., Zhang, Douglas, Smith, Andrew M., Moore, Jeffrey S., Kilian, Kristopher A.
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Sprache:eng
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Zusammenfassung:The generation of cell‐laden spatially organized 3D hydrogels is demonstrated by K. A. Kilian and co‐workers on page 5512, using macrophages and breast adenocarcinoma cells as a heterotypic model that mimics aspects of the tumor microenvironment. This versatile and tunable approach for fabricating soft materials in organized architectures may prove useful for engineering model systems for therapeutic development, and scaffolds for tissue engineering.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201570242