Biomaterials Discovery: Discovery of a Novel Polymer for Xeno‐Free, Long‐Term Culture of Human Pluripotent Stem Cell Expansion (Adv. Healthcare Mater. 6/2021)

In article number 2001448 by Morgan R. Alexander, Chris Denning, and co‐workers, a novel substrate for xeno‐free human pluripotent stem cell (hPSC) culture is discovered using a highthroughput multigenerational polymer microarray platform approach used to rapidly test over 600 polymers. This nanosca...

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Veröffentlicht in:Advanced healthcare materials 2021-03, Vol.10 (6), p.n/a
Hauptverfasser: Nasir, Aishah, Thorpe, Jordan, Burroughs, Laurence, Meurs, Joris, Pijuan‐Galito, Sara, Irvine, Derek J., Alexander, Morgan R., Denning, Chris
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Sprache:eng
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Zusammenfassung:In article number 2001448 by Morgan R. Alexander, Chris Denning, and co‐workers, a novel substrate for xeno‐free human pluripotent stem cell (hPSC) culture is discovered using a highthroughput multigenerational polymer microarray platform approach used to rapidly test over 600 polymers. This nanoscale phase separated blend of poly(tricyclodecane‐dimethanol diacrylate) and poly(butyl acrylate) (2:1 v/v) which supports hPSC expansion and differentiation after long‐term serial passage can be readily applied to common tissue culture plasticware.
ISSN:2192-2640
2192-2659
DOI:10.1002/adhm.202170019