Glucose‐Responsive Insulin Delivery: Microneedle‐Array Patch Fabricated with Enzyme‐Free Polymeric Components Capable of On‐Demand Insulin Delivery (Adv. Funct. Mater. 7/2019)

Glucose‐Responsive Insulin Delivery: Microneedle‐Array Patch Fabricated with Enzyme‐Free Polymeric Components Capable of On‐Demand Insulin Delivery (Adv. Funct. Mater. 7/2019)

In article number 1807369, Akira Matsumoto and co‐workers report an electronics‐free, enzyme‐free, and nanoparticle‐free smart artificial on‐skin pancreas, which is a hybrid microneedle‐array patch fabricated with a glucose‐sensitive boronate‐hydrogel and biocompatible silk fibroin semi‐interpenetra...

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Veröffentlicht in:Advanced functional materials 2019-02, Vol.29 (7), p.n/a
Hauptverfasser: Chen, Siyuan, Matsumoto, Hiroko, Moro‐oka, Yuki, Tanaka, Miyako, Miyahara, Yuji, Suganami, Takayoshi, Matsumoto, Akira
Format: Artikel
Sprache:eng
Schlagworte:
boronate hydrogel
closed‐loop
glucose‐responsive insulin delivery
microneedles
silk fibroin
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Zusammenfassung:In article number 1807369, Akira Matsumoto and co‐workers report an electronics‐free, enzyme‐free, and nanoparticle‐free smart artificial on‐skin pancreas, which is a hybrid microneedle‐array patch fabricated with a glucose‐sensitive boronate‐hydrogel and biocompatible silk fibroin semi‐interpenetrating network. This microneedles‐array patch could mimic the functionality of the pancreas and provide on‐demand insulin delivery in a safe, painless, and convenient way.
ISSN:1616-301X
1616-3028
DOI:10.1002/adfm.201970044