Drug Delivery: Dendron-Based Micelles for Topical Delivery of Endoxifen: A Potential Chemo-Preventive Medicine for Breast Cancer (Adv. Funct. Mater. 17/2014)

Drug Delivery: Dendron-Based Micelles for Topical Delivery of Endoxifen: A Potential Chemo-Preventive Medicine for Breast Cancer (Adv. Funct. Mater. 17/2014)

Surface‐modified dendron micelles (DMs) are developed on page 2442 by Seungpyo Hong and colleagues as a potential platform for topical delivery of endoxifen (EDX). The data indicates that skin permeation of EDX is highly dependent on the surface group of the DMs. In particular, carboxylated DMs exhi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Advanced functional materials 2014-05, Vol.24 (17), p.2441-2441
Hauptverfasser: Yang, Yang, Pearson, Ryan M., Lee, Oukseub, Lee, Chan-Woo, Chatterton Jr, Robert T., Khan, Seema A., Hong, Seungpyo
Format: Artikel
Sprache:eng
Schlagworte:
breast cancers
dendron micelles
drug delivery
endoxifen
human skin
topical delivery
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Surface‐modified dendron micelles (DMs) are developed on page 2442 by Seungpyo Hong and colleagues as a potential platform for topical delivery of endoxifen (EDX). The data indicates that skin permeation of EDX is highly dependent on the surface group of the DMs. In particular, carboxylated DMs exhibit significantly enhanced permeation of EDX through both mouse and human skin layers, offering a potential alternative administration route for chemoprevention.
ISSN:1616-301X
1616-3028
DOI:10.1002/adfm.201470109