Micropatterned Surfaces: Micropatterned Surfaces Expose the Coupling between Actin Cytoskeleton‐Lamin/Nesprin and Nuclear Deformability of Breast Cancer Cells with Different Malignancies (Adv. Biology 1/2021)

In article number 2000048, Vasif Hasirci, Ezgi Antmen, and Utkan Demirci present micropatterned surfaces that reveal the association between actin filaments, mechanotransduction, nuclear deformability, and cancer malignancy. The transparent micropatterned surfaces can be used as image analysis platf...

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Veröffentlicht in:Advanced biology 2021-01, Vol.5 (1), p.n/a
Hauptverfasser: Antmen, Ezgi, Demirci, Utkan, Hasirci, Vasif
Format: Artikel
Sprache:eng
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Zusammenfassung:In article number 2000048, Vasif Hasirci, Ezgi Antmen, and Utkan Demirci present micropatterned surfaces that reveal the association between actin filaments, mechanotransduction, nuclear deformability, and cancer malignancy. The transparent micropatterned surfaces can be used as image analysis platforms to provide robust, high throughput measurements of nuclear deformability of cancer cells, including the effect of cytoskeletal elements.
ISSN:2701-0198
2701-0198
DOI:10.1002/adbi.202170012