Interim Analyses During Group Sequential Clinical Trials

This JAMA Guide to Statistics and Methods describes why interim analyses are performed during group sequential trials, provides examples of the limitations of interim analyses, and provides guidance on interpreting the results of interim analyses performed during group sequential trials.

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Bibliographische Detailangaben
Veröffentlicht in:	JAMA : the journal of the American Medical Association 2021-10, Vol.326 (15), p.1524-1525
Hauptverfasser:	Meurer, William J, Tolles, Juliana
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute lymphoblastic leukemia Chemotherapy Children Clinical trials General & Internal Medicine Immunotherapy Leukemia Life Sciences & Biomedicine Lymphatic leukemia Lymphocytes B Medicine, General & Internal Science & Technology Survival
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	This JAMA Guide to Statistics and Methods describes why interim analyses are performed during group sequential trials, provides examples of the limitations of interim analyses, and provides guidance on interpreting the results of interim analyses performed during group sequential trials.
ISSN:	0098-7484 1538-3598
DOI:	10.1001/jama.2021.10174