Decreased adiponectin/leptin ratio relates to insulin resistance in adults with obesity
Adiponectin/leptin ratio, triacylglycerols, and waist-to-hip ratio explained almost half of HOMA-IR variance in the context of obesity. This study provides evidence to support adipose tissue dysfunction as a central feature of the pathophysiology of obesity and insulin resistance. Early identificati...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Castela, Inês Morais, Juliana Barreiros-Mota, Inês Silvestre, Marta P Marques, Cláudia Rodrigues, Catarina Ismael, Shámila Araújo, João R Ângelo-Dias, Miguel Martins, Catarina Borrego, Luís Miguel Monteiro, Rosário dos Santos Ribeiro F. Coutinho, Silvia Calhau, Conceição Alho Letra Martins, Catia Patricia Faria, Ana Pestana, Diogo Teixeira, Diana |
| description | Adiponectin/leptin ratio, triacylglycerols, and waist-to-hip ratio explained almost half of HOMA-IR variance in the context of obesity. This study provides evidence to support adipose tissue dysfunction as a central feature of the pathophysiology of obesity and insulin resistance. Early identification of individuals at higher risk of developing metabolic complications through adipose tissue dysfunction assessment and the staging of obesity and its transient phenotypes can contribute to improve therapeutic decision-making. |
| format | Article |
| fullrecord | <record><control><sourceid>cristin_3HK</sourceid><recordid>TN_cdi_cristin_nora_11250_3121867</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>11250_3121867</sourcerecordid><originalsourceid>FETCH-cristin_nora_11250_31218673</originalsourceid><addsrcrecordid>eNqNi0sKAjEQBbNxIeod2gOIZgY_ez94AMFlaDM92BA6Q7oH8fZG8ACuCl69mrr7iWIhVOoAOx6yUDSWdaKhAgoaZyiU0EjBMrDomL6ClNVQItWplmMyhRfbE_KjKnvP3aTHpLT4ceaWl_PteF3FUkOWILlg8L7ZbkLrG3_Y7dt_Ph-kfDov</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Decreased adiponectin/leptin ratio relates to insulin resistance in adults with obesity</title><source>NORA - Norwegian Open Research Archives</source><creator>Castela, Inês ; Morais, Juliana ; Barreiros-Mota, Inês ; Silvestre, Marta P ; Marques, Cláudia ; Rodrigues, Catarina ; Ismael, Shámila ; Araújo, João R ; Ângelo-Dias, Miguel ; Martins, Catarina ; Borrego, Luís Miguel ; Monteiro, Rosário ; dos Santos Ribeiro F. Coutinho, Silvia ; Calhau, Conceição ; Alho Letra Martins, Catia Patricia ; Faria, Ana ; Pestana, Diogo ; Teixeira, Diana</creator><creatorcontrib>Castela, Inês ; Morais, Juliana ; Barreiros-Mota, Inês ; Silvestre, Marta P ; Marques, Cláudia ; Rodrigues, Catarina ; Ismael, Shámila ; Araújo, João R ; Ângelo-Dias, Miguel ; Martins, Catarina ; Borrego, Luís Miguel ; Monteiro, Rosário ; dos Santos Ribeiro F. Coutinho, Silvia ; Calhau, Conceição ; Alho Letra Martins, Catia Patricia ; Faria, Ana ; Pestana, Diogo ; Teixeira, Diana</creatorcontrib><description>Adiponectin/leptin ratio, triacylglycerols, and waist-to-hip ratio explained almost half of HOMA-IR variance in the context of obesity. This study provides evidence to support adipose tissue dysfunction as a central feature of the pathophysiology of obesity and insulin resistance. Early identification of individuals at higher risk of developing metabolic complications through adipose tissue dysfunction assessment and the staging of obesity and its transient phenotypes can contribute to improve therapeutic decision-making.</description><language>eng</language><publisher>American Physiological Society</publisher><creationdate>2023</creationdate><rights>info:eu-repo/semantics/openAccess</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,780,885,26567</link.rule.ids><linktorsrc>$$Uhttp://hdl.handle.net/11250/3121867$$EView_record_in_NORA$$FView_record_in_$$GNORA$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Castela, Inês</creatorcontrib><creatorcontrib>Morais, Juliana</creatorcontrib><creatorcontrib>Barreiros-Mota, Inês</creatorcontrib><creatorcontrib>Silvestre, Marta P</creatorcontrib><creatorcontrib>Marques, Cláudia</creatorcontrib><creatorcontrib>Rodrigues, Catarina</creatorcontrib><creatorcontrib>Ismael, Shámila</creatorcontrib><creatorcontrib>Araújo, João R</creatorcontrib><creatorcontrib>Ângelo-Dias, Miguel</creatorcontrib><creatorcontrib>Martins, Catarina</creatorcontrib><creatorcontrib>Borrego, Luís Miguel</creatorcontrib><creatorcontrib>Monteiro, Rosário</creatorcontrib><creatorcontrib>dos Santos Ribeiro F. Coutinho, Silvia</creatorcontrib><creatorcontrib>Calhau, Conceição</creatorcontrib><creatorcontrib>Alho Letra Martins, Catia Patricia</creatorcontrib><creatorcontrib>Faria, Ana</creatorcontrib><creatorcontrib>Pestana, Diogo</creatorcontrib><creatorcontrib>Teixeira, Diana</creatorcontrib><title>Decreased adiponectin/leptin ratio relates to insulin resistance in adults with obesity</title><description>Adiponectin/leptin ratio, triacylglycerols, and waist-to-hip ratio explained almost half of HOMA-IR variance in the context of obesity. This study provides evidence to support adipose tissue dysfunction as a central feature of the pathophysiology of obesity and insulin resistance. Early identification of individuals at higher risk of developing metabolic complications through adipose tissue dysfunction assessment and the staging of obesity and its transient phenotypes can contribute to improve therapeutic decision-making.</description><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>3HK</sourceid><recordid>eNqNi0sKAjEQBbNxIeod2gOIZgY_ez94AMFlaDM92BA6Q7oH8fZG8ACuCl69mrr7iWIhVOoAOx6yUDSWdaKhAgoaZyiU0EjBMrDomL6ClNVQItWplmMyhRfbE_KjKnvP3aTHpLT4ceaWl_PteF3FUkOWILlg8L7ZbkLrG3_Y7dt_Ph-kfDov</recordid><startdate>2023</startdate><enddate>2023</enddate><creator>Castela, Inês</creator><creator>Morais, Juliana</creator><creator>Barreiros-Mota, Inês</creator><creator>Silvestre, Marta P</creator><creator>Marques, Cláudia</creator><creator>Rodrigues, Catarina</creator><creator>Ismael, Shámila</creator><creator>Araújo, João R</creator><creator>Ângelo-Dias, Miguel</creator><creator>Martins, Catarina</creator><creator>Borrego, Luís Miguel</creator><creator>Monteiro, Rosário</creator><creator>dos Santos Ribeiro F. Coutinho, Silvia</creator><creator>Calhau, Conceição</creator><creator>Alho Letra Martins, Catia Patricia</creator><creator>Faria, Ana</creator><creator>Pestana, Diogo</creator><creator>Teixeira, Diana</creator><general>American Physiological Society</general><scope>3HK</scope></search><sort><creationdate>2023</creationdate><title>Decreased adiponectin/leptin ratio relates to insulin resistance in adults with obesity</title><author>Castela, Inês ; Morais, Juliana ; Barreiros-Mota, Inês ; Silvestre, Marta P ; Marques, Cláudia ; Rodrigues, Catarina ; Ismael, Shámila ; Araújo, João R ; Ângelo-Dias, Miguel ; Martins, Catarina ; Borrego, Luís Miguel ; Monteiro, Rosário ; dos Santos Ribeiro F. Coutinho, Silvia ; Calhau, Conceição ; Alho Letra Martins, Catia Patricia ; Faria, Ana ; Pestana, Diogo ; Teixeira, Diana</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-cristin_nora_11250_31218673</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Castela, Inês</creatorcontrib><creatorcontrib>Morais, Juliana</creatorcontrib><creatorcontrib>Barreiros-Mota, Inês</creatorcontrib><creatorcontrib>Silvestre, Marta P</creatorcontrib><creatorcontrib>Marques, Cláudia</creatorcontrib><creatorcontrib>Rodrigues, Catarina</creatorcontrib><creatorcontrib>Ismael, Shámila</creatorcontrib><creatorcontrib>Araújo, João R</creatorcontrib><creatorcontrib>Ângelo-Dias, Miguel</creatorcontrib><creatorcontrib>Martins, Catarina</creatorcontrib><creatorcontrib>Borrego, Luís Miguel</creatorcontrib><creatorcontrib>Monteiro, Rosário</creatorcontrib><creatorcontrib>dos Santos Ribeiro F. Coutinho, Silvia</creatorcontrib><creatorcontrib>Calhau, Conceição</creatorcontrib><creatorcontrib>Alho Letra Martins, Catia Patricia</creatorcontrib><creatorcontrib>Faria, Ana</creatorcontrib><creatorcontrib>Pestana, Diogo</creatorcontrib><creatorcontrib>Teixeira, Diana</creatorcontrib><collection>NORA - Norwegian Open Research Archives</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Castela, Inês</au><au>Morais, Juliana</au><au>Barreiros-Mota, Inês</au><au>Silvestre, Marta P</au><au>Marques, Cláudia</au><au>Rodrigues, Catarina</au><au>Ismael, Shámila</au><au>Araújo, João R</au><au>Ângelo-Dias, Miguel</au><au>Martins, Catarina</au><au>Borrego, Luís Miguel</au><au>Monteiro, Rosário</au><au>dos Santos Ribeiro F. Coutinho, Silvia</au><au>Calhau, Conceição</au><au>Alho Letra Martins, Catia Patricia</au><au>Faria, Ana</au><au>Pestana, Diogo</au><au>Teixeira, Diana</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Decreased adiponectin/leptin ratio relates to insulin resistance in adults with obesity</atitle><date>2023</date><risdate>2023</risdate><abstract>Adiponectin/leptin ratio, triacylglycerols, and waist-to-hip ratio explained almost half of HOMA-IR variance in the context of obesity. This study provides evidence to support adipose tissue dysfunction as a central feature of the pathophysiology of obesity and insulin resistance. Early identification of individuals at higher risk of developing metabolic complications through adipose tissue dysfunction assessment and the staging of obesity and its transient phenotypes can contribute to improve therapeutic decision-making.</abstract><pub>American Physiological Society</pub><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_cristin_nora_11250_3121867 |
| source | NORA - Norwegian Open Research Archives |
| title | Decreased adiponectin/leptin ratio relates to insulin resistance in adults with obesity |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-19T04%3A05%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-cristin_3HK&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Decreased%20adiponectin/leptin%20ratio%20relates%20to%20insulin%20resistance%20in%20adults%20with%20obesity&rft.au=Castela,%20In%C3%AAs&rft.date=2023&rft_id=info:doi/&rft_dat=%3Ccristin_3HK%3E11250_3121867%3C/cristin_3HK%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |