Perceptions of generic medicines and medication adherence after percutaneous coronary intervention: a prospective multicentre cohort study

Objective: To determine patient perceptions of generic medicines 2 and 6 months after percutaneous coronary intervention (PCI), and to determine whether these perceptions moderate medication adherence. Design: Prospective multicentre cohort study with repeated measures of perceptions of generic medi...

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Hauptverfasser: Pettersen, Trond Røed, Schjøtt, Jan Didrik, Allore, Heather G, Bendz, Bjørn, Borregaard, Britt, Fridlund, Bengt Gotthard Anton, Larsen, Alf Inge, Nordrehaug, Jan Erik, Rotevatn, Svein, Wentzel-Larsen, Tore, Norekvål, Tone Merete
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Sprache:eng
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Zusammenfassung:Objective: To determine patient perceptions of generic medicines 2 and 6 months after percutaneous coronary intervention (PCI), and to determine whether these perceptions moderate medication adherence. Design: Prospective multicentre cohort study with repeated measures of perceptions of generic medicines and medication adherence. Setting: The CONCARDPCI study conducted at seven large referral PCI centres in Norway and Denmark between June 2017 and May 2020. Participants: A total of 3417 adults (78% men), using both generic and brand name medicines, with a mean age of 66 years (SD 11) who underwent PCI were followed up 2 and 6 months after discharge from hospital. Main outcome measures: Perceptions of generic medicines were the main outcome. The secondary outcome was medication adherence. Results: Perceptions of generic medicines were significantly more negative at 2 than at 6 months (1.10, 95% CI 0.41 to 1.79, p=0.002). Female sex (−4.21, 95% CI −6.75 to −1.71, p=0.001), older age (−0.12, 95% CI −0.23 to −0.02, p=0.020), lower education level (overall p