Clinical features of suspected Ebola cases referred to the Moyamba ETC, Sierra Leone: Challenges in the later stages of the 2014 outbreak

Background The last ebola virus disease (EVD) outbreak has been the most important since 1976. EVD cases decreased drastically in Sierra Leone at the beginning of 2015. We aim to determine the clinical findings and evolution of patients admitted to an Ebola treatment center (ETC) during the epidemic...

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Hauptverfasser: Arranz, Javier, Lundeby, Karen Marie, Hassan, Shoaib, Fuentes, Luis Matías Zabala, Garcés, Pedro San José, Haaskjold, Yngvar Lunde, Bolkan, Håkon Angell, Krogh, Kurt, Jongopi, James, Mellesmo, Sindre, Jøsendal, Ola, Øpstad, Åsmund, Svensen, Erling, Kamara, Alfred Sandy, Roberts, David P, Stamper, Paul D, Austin, Paula, Moosa, Alfredo J, Marke, Dennis, Berg, Åse, Blomberg, Bjørn, Riera, Melcior
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Sprache:eng
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Zusammenfassung:Background The last ebola virus disease (EVD) outbreak has been the most important since 1976. EVD cases decreased drastically in Sierra Leone at the beginning of 2015. We aim to determine the clinical findings and evolution of patients admitted to an Ebola treatment center (ETC) during the epidemic’s late phase. Methods We analyze retrospectively data of patients admitted to the Moyamba ETC (December 2014-March 2015). Patients were classified in EVD or non-EVD patients according to the results of Ebola virus real-time reverse transcription polymerase chain reaction (ZAIRE-RT-PCR). Results Seventy-five patients were included, 41.3 % were positive for ZAIRE-RT-PCR. More women (68 % vs 28 %, p = 0.001) were EVD-positive. More EVD patients had previous contact with an Ebola patient (74.2 % vs 36.3 %, p