T1 bladder cancer in Norway: treatment and survival

Aim: Evaluation of treatment and survival of pT1 stage (T1) bladder cancer (BC) patients diagnosed with transitional cell carcinoma of the urinary bladder in Norway. Material and methods: According to the Cancer Registry of Norway, 1,108 patients were diagnosed with T1 BC between 2008-2012. Informat...

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Hauptverfasser: Blindheim, Augun Jodis, Fosså, Sophie Dorothea, Babigumira, Ronnie, Myklebust, Tor Åge, Haug, Erik Skaaheim, Arum, Carl-Jørgen, Kulle, Bettina
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Sprache:eng
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Zusammenfassung:Aim: Evaluation of treatment and survival of pT1 stage (T1) bladder cancer (BC) patients diagnosed with transitional cell carcinoma of the urinary bladder in Norway. Material and methods: According to the Cancer Registry of Norway, 1,108 patients were diagnosed with T1 BC between 2008-2012. Information on surgical and medical procedures was provided by the Norwegian Patients Registry. Regression and survival models were applied to characterize patients receiving bacillus Calmette-Guerin (BCG) and radical cystectomy (RC) as early and delayed treatment and to estimate overall and cause specific survival rates (OS; CSS). Adjustments for sex, age, WHO grade and concomitant cis were made. Results: In total, 449 (41%) patients received BCG treatment, 162 (15%) as early treatment. RC represented the early treatment in 96 (9%) patients and the delayed treatment in 84 (8%). Overall, 850 (77%) patients received neither BCG nor RC as early treatment, of whom 287 (26%) were treated with BCG and 66 (6%) with RC during follow-up. Patients