The marine biodiscovery pipeline and ocean medicines of tomorrow

Marine organisms possess the capacity to produce a variety of unique and biologically potent natural products for treating human diseases, many of which are currently commercially available or are in advanced clinical trials. Here we provide a short review on progress in the field and discuss a case...

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Veröffentlicht in:	Journal of the Marine Biological Association of the United Kingdom 2016-02, Vol.96 (1), p.151-158
Hauptverfasser:	Jaspars, Marcel, De Pascale, Donatella, Andersen, Jeanette H., Reyes, Fernando, Crawford, Alexander D., Ianora, Adrianna
Format:	Artikel
Sprache:	eng
Schlagworte:	Agriculture and fishery disciplines: 900 Cancer therapies Cardiovascular disease Clinical trials Drugs Fisheries science: 920 Fiskerifag: 920 Infections Landbruks- og Fiskerifag: 900 Lymphoma Marine Marine organisms Microorganisms Natural products Organisms Pharmaceutical industry VDP
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Beschreibung
Zusammenfassung:	Marine organisms possess the capacity to produce a variety of unique and biologically potent natural products for treating human diseases, many of which are currently commercially available or are in advanced clinical trials. Here we provide a short review on progress in the field and discuss a case study of an EU-funded project, PharmaSea, which aims to discover novel products for the treatment of infections, inflammation and neurodegenerative diseases. Research in this sector is opening new doors for harnessing the potential of marine natural products with pharmaceutical properties.
ISSN:	0025-3154 1469-7769 1469-7769
DOI:	10.1017/S0025315415002106