A STUDY OF NANOSECOND FLUORESCENCE SPECTROSCOPY OF HEMOGLOBIN M

A STUDY OF NANOSECOND FLUORESCENCE SPECTROSCOPY OF HEMOGLOBIN M

<正> Hemoglobin M (HbM) is one kind of abnormal hemoglobin which leads to the genetic methemoglobin disease. So far five hemoglobins M have been already reported. The hemoglobin M we studied in this note was found in Shanghai. It was confirmed that the hemoglobin was the HbMIwat (87 (FS...

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Veröffentlicht in:科学通报：英文版 1984 (12), p.1695-1699
1. Verfasser: 连少辉 阮康成 江寿平 程观炽 任兆瑞 曾溢滔
Format: Artikel
Sprache:eng
Schlagworte:
hemoglobin
histidine
Hemoglobin
ferric
replaced
abnormal
dialysis
genet
Weber
lifetime
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Zusammenfassung:<正> Hemoglobin M (HbM) is one kind of abnormal hemoglobin which leads to the genetic methemoglobin disease. So far five hemoglobins M have been already reported. The hemoglobin M we studied in this note was found in Shanghai. It was confirmed that the hemoglobin was the HbMIwat (87 (FS) IIis→Tyr) by analyzing its amino acid sequence. The histidine in the position 87 of the a chain in this abnormal hemoglobin is replaced by tyrosine, the iron atom of heme is in ferric state and the hemoglobin becomes methe-
ISSN:2095-9273