Synthesis and bioactivity of 4-quinazoline oxime ethers

Synthesis and bioactivity of 4-quinazoline oxime ethers

<正> Quinazoline derivatives are well known for their wide range of bio-logical activities.At the same time oxime derivatives, oxime ethers,are biologically important. But there is no reported examples ofquinazolines with oxime ether functionality at 4-position. It was there-fore meanin...

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Veröffentlicht in:自然科学进展：英文版 1998 (3), p.104-110
Hauptverfasser: 李慧英, 黄润秋, 邱德文, 杨昭, 刘昕, 马军安, 马志华
Format: Artikel
Sprache:eng
Schlagworte:
ethers
virucides
synthesis
quinazolines
oxime
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Zusammenfassung:<正> Quinazoline derivatives are well known for their wide range of bio-logical activities.At the same time oxime derivatives, oxime ethers,are biologically important. But there is no reported examples ofquinazolines with oxime ether functionality at 4-position. It was there-fore meaningful to synthesize the title compounds (fig. 1) by incorpo-
ISSN:1002-0071