Ginseng saponin Rbl enhances hematopoietic function and dendritic cells differentiation
Ginsenoside Rbl （GRbl） is the main active ingrediem of the trad- itional Chinese medicine ginseng and exhibits broad pharmaceutical activities. GRbl can significantly stimulate haematopoietic function and enhance T lymphocyte proliferation and differentiation [1,2]. Shengxueling capsules, in which t...
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| Veröffentlicht in: | 生物化学与生物物理学报：英文版 2017, Vol.49 (8), p.746-749 |
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| container_title | 生物化学与生物物理学报：英文版 |
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| creator | Li Zhang Hui Feng Yibo He Jinfang Zhao Yimin Chen Yonglin Liu |
| description | Ginsenoside Rbl （GRbl） is the main active ingrediem of the trad- itional Chinese medicine ginseng and exhibits broad pharmaceutical activities. GRbl can significantly stimulate haematopoietic function and enhance T lymphocyte proliferation and differentiation [1,2]. Shengxueling capsules, in which the main ingredient is GRbl, have positive effects on the treatment of severe aplastic anemia （AA） [3,4], but the mechanism remains unknown. Tu et al. [5] demon- strated that the expression of the co-stimulatory molecules CD80 and CD86 on the surface of dendritic cells （DCs） was significantly higher in severe AA patients than in normal populations. In add- ition, the antigen-presenting abilities of the DCs were increased, |
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GRbl can significantly stimulate haematopoietic function and enhance T lymphocyte proliferation and differentiation [1,2]. Shengxueling capsules, in which the main ingredient is GRbl, have positive effects on the treatment of severe aplastic anemia （AA） [3,4], but the mechanism remains unknown. Tu et al. [5] demon- strated that the expression of the co-stimulatory molecules CD80 and CD86 on the surface of dendritic cells （DCs） was significantly higher in severe AA patients than in normal populations. In add- ition, the antigen-presenting abilities of the DCs were increased,</description><identifier>ISSN: 1672-9145</identifier><identifier>EISSN: 1745-7270</identifier><language>eng</language><subject>T淋巴细胞 ; 人参皂苷Rb1 ; 共刺激分子 ; 再生障碍性贫血 ; 树突状细胞 ; 细胞分化 ; 药理活性 ; 造血功能</subject><ispartof>生物化学与生物物理学报：英文版, 2017, Vol.49 (8), p.746-749</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/90160X/90160X.jpg</thumbnail><link.rule.ids>315,781,785,4025</link.rule.ids></links><search><creatorcontrib>Li Zhang;Hui Feng;Yibo He;Jinfang Zhao;Yimin Chen;Yonglin Liu</creatorcontrib><title>Ginseng saponin Rbl enhances hematopoietic function and dendritic cells differentiation</title><title>生物化学与生物物理学报：英文版</title><addtitle>Acta Biochimica et Biophysica Sinica</addtitle><description>Ginsenoside Rbl （GRbl） is the main active ingrediem of the trad- itional Chinese medicine ginseng and exhibits broad pharmaceutical activities. 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GRbl can significantly stimulate haematopoietic function and enhance T lymphocyte proliferation and differentiation [1,2]. Shengxueling capsules, in which the main ingredient is GRbl, have positive effects on the treatment of severe aplastic anemia （AA） [3,4], but the mechanism remains unknown. Tu et al. [5] demon- strated that the expression of the co-stimulatory molecules CD80 and CD86 on the surface of dendritic cells （DCs） was significantly higher in severe AA patients than in normal populations. In add- ition, the antigen-presenting abilities of the DCs were increased,</abstract></addata></record> |
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| ispartof | 生物化学与生物物理学报：英文版, 2017, Vol.49 (8), p.746-749 |
| issn | 1672-9145 1745-7270 |
| language | eng |
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| source | EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | T淋巴细胞 人参皂苷Rb1 共刺激分子 再生障碍性贫血 树突状细胞 细胞分化 药理活性 造血功能 |
| title | Ginseng saponin Rbl enhances hematopoietic function and dendritic cells differentiation |
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