ixed Dubin-Gilbert Syndrome： A Compound Heterozygous Phenotype of Two Novel Variants in ABCC2 Gene

Gilbert syndrome （GS, MIM #143500） is characterized by fluctuating mild, unconjugated hyperbilirubinemia 〈85 μmol/L and is caused by mutations in the bilirubin uridine diphosphate （UDP）-glucuronosyltransferase gene （ UGT1A 1 ）,Dubin-Johnson syndrome （DJS, M I M #237500） is characterized by fluctuating mild, predominantly conjugated hyperbilirubinemia and is caused by mutations in the ATP-binding cassette subfamily C member 2 gene （ABCC2）.