Enzyme-catalyzed direct three-component aza-Diels–Alder reaction using lipase from Candida sp.99–125

Enzyme-catalyzed direct three-component aza-Diels–Alder reaction using lipase from Candida sp.99–125

The direct three-component aza-Diels–Alder reaction was conducted with lipase as a catalyst for the first time. Under the optimized conditions, the aza-Diels–Alder reaction catalyzed by lipase from Candida sp.99–125 provided the products in moderate to excellent yields. Meanwhile, the endo/exo ratio...

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Veröffentlicht in:中国化学快报：英文版 2017, Vol.28 (1), p.153-158
1. Verfasser: Dong-Hang Yin Wei Liu Zhi-Xiang Wang Xin Huang Jing Zhang De-Chun Huang
Format: Artikel
Sprache:eng
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Zusammenfassung:The direct three-component aza-Diels–Alder reaction was conducted with lipase as a catalyst for the first time. Under the optimized conditions, the aza-Diels–Alder reaction catalyzed by lipase from Candida sp.99–125 provided the products in moderate to excellent yields. Meanwhile, the endo/exo ratio reached up to 88：12.
ISSN:1001-8417
1878-5964