The PilZ domain of MrkH represents a nove ）NA binding motif

The PilZ domain of MrkH represents a nove ）NA binding motif

MrkH is the first characterized c-di-GMP related transcrip- tional regulator which affects type 3 fimbrial expression in response to cellular c-di-GMP level, and thus plays an important role in the biofilm formation of Klebsiella pneu- moniae （Murphy and Clegg, 2012; Wilksch et al., 2011）. However,...

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Veröffentlicht in:蛋白质与细胞：英文版 2016 (10), p.766-772
1. Verfasser: Feng Wang Qing He Kaixuan Su Fei Gao Yan Huang Zong Lin Deyu Zhu Lichuan Gu
Format: Artikel
Sprache:eng
Schlagworte:
DNA序列
生物膜
细胞
肺炎克雷伯菌
转录
钠
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Zusammenfassung:MrkH is the first characterized c-di-GMP related transcrip- tional regulator which affects type 3 fimbrial expression in response to cellular c-di-GMP level, and thus plays an important role in the biofilm formation of Klebsiella pneu- moniae （Murphy and Clegg, 2012; Wilksch et al., 2011）. However, how MrkH recognizes c-di-GMP and the target DNA sequence remains obscure.
ISSN:1674-800X
1674-8018