Management of hepatocellular carcinoma： Predictive valueof immunohistochemical markers for postoperative survival

Hepatocellular carcinoma （HCC） accounts for over 90%of all primary liver cancers. With an ever increasingincidence trend year by year, it has become the thirdmost common cause of death from cancer worldwide.Hepatic resection is generally considered to be one ofthe most effective therapies for HCC patients, however,there is a high risk of recurrence in postoperativeHCC. In clinical practice, there exists an urgent needfor valid prognostic markers to identify patientswith prognosis, hence the importance of studies onprognostic markers in improving the prediction of HCCprognosis. This review focuses on the most promisingimmunohistochemical prognostic markers in predictingthe postoperative survival of HCC patients.