Stem cell therapy in inflammatory bowel disease: Apromising therapeutic strategy

Inflammatory bowel diseases are inflammatory, chronicand progressive diseases of the intestinal tract forwhich no curative treatment is available. Research inother fields with stem cells of different sources and withimmunoregulatory cells (regulatory T-lymphocytes anddendritic T-cells) opens up new...

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Veröffentlicht in:世界干细胞杂志:英文版(电子版) 2015 (2), p.343-351
1. Verfasser: Ana I Flores Gonzalo J Gómez-Gómez ángeles Masedo-González M Pilar Martínez-Montiel
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Sprache:eng
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Zusammenfassung:Inflammatory bowel diseases are inflammatory, chronicand progressive diseases of the intestinal tract forwhich no curative treatment is available. Research inother fields with stem cells of different sources and withimmunoregulatory cells (regulatory T-lymphocytes anddendritic T-cells) opens up new expectations for theiruse in these diseases. The goal for stem cell-basedtherapy is to provide a permanent cure. To achieve this,it will be necessary to obtain a cellular product, originalor genetically modified, that has a high migrationcapacity and homes into the intestine, has high survivalafter transplantation, regulates the immune reactionwhile not being visible to the patient's immune system,and repairs the injured tissue.
ISSN:1948-0210
1948-0210