Convenient synthesis of bis(indolyl)alkanes by dithiocarbohydrazone Schiff basefZn(ClO4)2.6H20 catalyzed Friedel-Crafts reaction of indoles with imines
A new, convenient and excellent yield procedure for the preparation of bis(indolyl)methanes (BIMs) by Friedel-Crafts reaction of indoles with imines in the presence of dithiocarbohydrazone Schiff base/ Zn(CIO4)2.6H2O as a highly stable, effective and readily available catalyst is described. Moderate...
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Veröffentlicht in: | 中国化学快报:英文版 2014 (1), p.163-165 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | A new, convenient and excellent yield procedure for the preparation of bis(indolyl)methanes (BIMs) by Friedel-Crafts reaction of indoles with imines in the presence of dithiocarbohydrazone Schiff base/ Zn(CIO4)2.6H2O as a highly stable, effective and readily available catalyst is described. Moderate to good yields (up to 99% yield) were obtained with both substrates for imine derivatives. This procedure is simple, practical and economic. |
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ISSN: | 1001-8417 1878-5964 |