First total synthesis of a naturally occurring nucleoside disulfide： 9-（5＇-Deoxy-51-thio-β-D-xylofuranosyl）adenine disulfide

A naturally occurring nucleoside disulfide, 9-（51-deoxy-5t-thio-β-D-xylofuranosyl）adenine disulfide, was first synthesized from o-xylose over 7 steps in 20% overall yield. The key step involved Vorbri.iggen glycosylation of silylated N6-benzoyladenine with xylose diacetate moiety.

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Bibliographische Detailangaben
Veröffentlicht in:	中国化学快报：英文版 2012, Vol.23 (9), p.996-998
1. Verfasser:	Hai Xin Ding Ling Cui Da Ru Chun Yang Ban Peng Cao Qi Sun Qiang Xiao
Format:	Artikel
Sprache:	eng
Schlagworte:	二硫化物呋喃总合成核苷硫代糖基化腺嘌呤自然
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Beschreibung
Zusammenfassung:	A naturally occurring nucleoside disulfide, 9-（51-deoxy-5t-thio-β-D-xylofuranosyl）adenine disulfide, was first synthesized from o-xylose over 7 steps in 20% overall yield. The key step involved Vorbri.iggen glycosylation of silylated N6-benzoyladenine with xylose diacetate moiety.
ISSN:	1001-8417 1878-5964